✷ The Root of Thought: Unlocking Glia--The Brain Cell That Will Help Us Sharpen Our Wits, Heal Injury, and Treat Brain Disease Epub ✺ Author Andrew Koob – Thomashillier.co.uk

The Root of Thought: Unlocking Glia--The Brain Cell That Will Help Us Sharpen Our Wits, Heal Injury, and Treat Brain Disease Until Recently, Neuroscientists Thought Glial Cells Did Little Than Hold Your Brain Together But In The Past Few Years, They Ve Discovered That Glial Cells Are Extraordinarily Important In Fact, They May Hold The Key To Understanding Intelligence, Treating Psychiatric Disorders And Brain Injuries And Perhaps Even Curing Fatal Conditions Like Alzheimer S, Parkinson S, And Lou Gehrig S Disease In The Root Of Thought, Leading Neuroscientist Dr Andrew Koob Reveals What We Ve Learned About These Remarkable Cells, From Their Unexpected Role In Information Storage To Their Function As Adult Stem Cells That Can Keep Your Brain Growing And Adapting Longer Than Scientists Ever Imagined Possible Ranging From Fruit Flies To Einstein, Koob Reveals The Surprising Correlation Between Intelligence And The Brain S Percentage Of Glial Cells And Why These Cells Unique Wavelike Communications May Be Especially Conducive To The Fluid Information Processing Human Beings Depend Upon You Ll Learn How Crucial Glial Cells Grow And Develop Why Almost All Brain Tumors Are Comprised Of Glial Cells And The Potential Implications For Treatment Even The Apparent Role Of Glial Cells In Your Every Thought And Dream


10 thoughts on “The Root of Thought: Unlocking Glia--The Brain Cell That Will Help Us Sharpen Our Wits, Heal Injury, and Treat Brain Disease

  1. says:

    Kitap asl nda T rk e ye evirildi i gibi D ncenin K keni hakk nda diyemeyiz Orijinal isminde oldu u zere Unlocking Glia the Brain Cell That Will Help Us Sharpen Our Wits, Heal Injury, and Treat Brain Disease yani beyindeki Glia h creleri hakk nda asl nda.Kitab sat n alacaklar, okumak isteyecekler bunu g z n nde bulundurarak okumal Yaratt izlenimin aksine, pop ler bilim kitab demek de zor Bunun yerine kitab en iyi tan mlayacak ey N ron merkezli N roloji isminden de anla Kitap asl nda T rk e ye evirildi i gibi D ncenin K keni hakk nda diyemeyiz Orijinal isminde oldu u zere Unlocking Glia the Brain Cell That Will Help Us Sharpen Our Wits, Heal Injury, and Treat Brain Disease yani beyindeki Glia h creleri hakk nda asl nda.Kitab sat n alacaklar, okumak isteyecekler bunu g z n nde bulundurarak okumal Yaratt izlenimin aksine, pop ler bilim kitab demek de zor Bunun yerine kitab en iyi tan mlayacak ey N ron merkezli N roloji isminden de anla laca zere art k eskimi tir ve beynimizin sadece %10 unu kullan yoruz gibi eylerin modas ge mi tir diyebiliriz Kitapta uzun zaman n rolojinin yaln zca n rona odakland n bu nedenle beyin hastal klar n , hasarlar n anlamam z da gecikmi tir temas zerine durulmu.Bu ba lamda, okunmas art de il ancak retici ve faydal


  2. says:

    I recently read The Root of Thought by Andrew Koob , expecting to get better insight on the role of glial cells in the brain, billed as potentiallythan just critical to housekeeping in the brain, of which they comprise 90% Unfortunately, although the author seems to be a somewhat well credentialed young investigator of neuroscience, he doesn t make a compelling case that glia, in particular, astrocytes, as the root of thought Although he made some interesting claims, such as about the po I recently read The Root of Thought by Andrew Koob , expecting to get better insight on the role of glial cells in the brain, billed as potentiallythan just critical to housekeeping in the brain, of which they comprise 90% Unfortunately, although the author seems to be a somewhat well credentialed young investigator of neuroscience, he doesn t make a compelling case that glia, in particular, astrocytes, as the root of thought Although he made some interesting claims, such as about the potential importance of calcium waves in the brain, and the anecdotal example of the increased concentration of astrocytes in Einstein s brain in his right parietal and frontal lobes where presumably quantitative reasoning may be concentrated , his bold pronouncement that glial cells are the real genesis of our thoughts, is unsupported and without any hint of any hypothetical mechanism We know that nonlinear circuit models of neurons consistent with many in situ observations can be assembled in very effective and sophisticated networks to do all sorts of complex adaptive tasks, but I don t know of any equivalent development and demonstration of a theoretical model of astrocytes That s not to say that glial cells don t have an undiscovered function other than housekeeping, where they have been relegated for almost a century, or that they don t have a potentially integral, albeit complex and synergistic role in conjunction with neurons, but Koob has not established his case


  3. says:

    In any case research should be doneabout glial cells, the neuron doctrine cajal may be wrong , may be the neuron glial doctrine glogi wrong too , days will show that.


  4. says:

    Wow I love this bookSo it s very probable that it s Glia, specifically astrocytes, that are at the root of our deep thinking, imagination, and creativity, etcI enjoyed how information dense this was too, all the while keeping the mood up with vivid little analogies and sprinkles of humor.


  5. says:

    very poorly edited it s a collection of notes put together to make a book.


  6. says:

    Good starter for neuroscience, like mini pita or spicy mash It begins from the cells neurons, glial cells to explanations of neurological diseases I wouldn t think that a neuroscience book give satisfaction both college level and public people Ayn f nd k pide ya da ac l ezme gibi, sinirbilime iyi bir ba lang Sinir h crelerinden n ron ve glialar ba lay p n rolojik hastal klar n a klamas na kadar ok g zel anlat yor Bir sinirbilim kitab n n hem niversite seviyesi hem de genel ins Good starter for neuroscience, like mini pita or spicy mash It begins from the cells neurons, glial cells to explanations of neurological diseases I wouldn t think that a neuroscience book give satisfaction both college level and public people Ayn f nd k pide ya da ac l ezme gibi, sinirbilime iyi bir ba lang Sinir h crelerinden n ron ve glialar ba lay p n rolojik hastal klar n a klamas na kadar ok g zel anlat yor Bir sinirbilim kitab n n hem niversite seviyesi hem de genel insan bu kadar tatmin edece ini d nmezdim


  7. says:

    Koob challenges a century of what he calls the Neuron Religion, which excludes 90% of brain matter, the glia cells, that are tossed aside as filler, brain matter Koob states that neurons take in sensory input related to energy gathering and procreation and express motor output that is directed toward these objectives Without glia cells, sensory input and motor output is reflexive in the stimulus response mode and function without the inhibition of thinking Inbetween input and output lies Koob challenges a century of what he calls the Neuron Religion, which excludes 90% of brain matter, the glia cells, that are tossed aside as filler, brain matter Koob states that neurons take in sensory input related to energy gathering and procreation and express motor output that is directed toward these objectives Without glia cells, sensory input and motor output is reflexive in the stimulus response mode and function without the inhibition of thinking Inbetween input and output lies a black box, the glia cells and the astrocytes specifically, that mediate input and output with information storage and processing He argues that these cells, not neurons, are the root of thought the pondering cell.As part of information processing, Koob believes that astrocytes are primary and neurons are secondary in the sense that astrocytes communicate and direct the neurons Communication among glia cells and between glia cells and neurons occurs, he says, through calcium waves Unlike neurons, these cells can regenerate with use througout life this capacity for regeneration is why 60 70% of brain tumors he says are of astrocyte origin The percentage of glia cells grows as one moves up the evolutinary ladder With 90% of brain matter in humans 80% for chimps 20% for the fruit fly , this is the relatively distinctive function of the human brain.Koob notes that neurons have their roots in the evolutionary reflex to procreate and get food The use of reflex is misleading as it suggests that life reacts to the world It does of course, but it reacts because it needs to act to find energy and to procreate Life, in other words, is first and foremost an outgoing, acting force reacting is where adjusting to environmental stimuli and learning and reasoning come into the picture Koob s reference to the glia cells as the blackbox of the brain is a richer problem than he lets on as he does not touch upon how the physiological processes involved with energy seeking, procreation and relevant environmental stimuli are transformed into mental representations that allow for learning, mental manipulation, and self regulation Considering the technical nature of the subject, Koob is clear, humorous and void of vitriolic comments despite his obvious problem with the Neuron Doctrine Whether he s onto something, we have to leave that to the medical and scientific professionals Given the emphasis on neuromedicine and neuroscience, that may continue to be a challenge


  8. says:

    Last week I felt like reading something about popular science, so I went down to the library and randomly picked up this book Maybe because I know almost nothing about brain science, I thought this book was hilarious It is basically an angry rant about how unfair it is that all these years neurons have received all the attention in brain research, while the other cells that make up our brains, glia, have been wrongly ignored by scientists This subversive theory essentially proposes that, even Last week I felt like reading something about popular science, so I went down to the library and randomly picked up this book Maybe because I know almost nothing about brain science, I thought this book was hilarious It is basically an angry rant about how unfair it is that all these years neurons have received all the attention in brain research, while the other cells that make up our brains, glia, have been wrongly ignored by scientists This subversive theory essentially proposes that, even though we know that 10% of our brain cells are neurons, and the other 90% are glia, scientists have, until now, considered neurons to be the main cells, the ones that did all the work, all the thinking, remembering, telling the body to function etc, while glia cells served simply as a kind of insulator or padding for neurons electrical impulses or something like that anyway However, according to Andrew Koob, recent research suggests it might be possible that glial cells are actually the ones that do all the work, while neurons are simply the highways that connect them It is funny because the author takes such a personal and angry tone while explaining his theory that it would seem he is defending some oppressed community that has been ruthlessly abused and repressed for years by evil forces In his defence of poor glia, he relentlessly insults and makes fun of those neuroscientists he thinks responsible for the neglect in the study of glia cells Ramon y Cajal mainly, who he considers to have been some kind of arrogant, amoral scientist, manipulative and capable of despicable acts.In general, the book is not that well written, it gets confusing and vague at points, but I give it three stars because the author is so passionate about his subject I feel like I have been converted to his cause Down with the idolatry of the neuron


  9. says:

    Humor injected throughout made thisenjoyable while covering the topic of the neglected glial cells The brain research history in the beginning was a bit of a slog I wasinterested in the research related to psychiatric disorders, degenerative brain disease, traumatic brain injury and brain cancer As glial cells may explain intelligence, creativity Imagination and dreams, I hope there will beresearch funding in this area instead of primarily focusing on the neurons This book Humor injected throughout made thisenjoyable while covering the topic of the neglected glial cells The brain research history in the beginning was a bit of a slog I wasinterested in the research related to psychiatric disorders, degenerative brain disease, traumatic brain injury and brain cancer As glial cells may explain intelligence, creativity Imagination and dreams, I hope there will beresearch funding in this area instead of primarily focusing on the neurons This book is for those who care about a scientific basis, but are willing to tolerate a dearth of information and a plea forresearch in this area, along with a paradigm shift


  10. says:

    The title is a bit misleading, the focus here is glia how it works and what we know, but if you are interested in neuroscience and biology at a fundamental level it will deliver The speculation is bold and the truth will likely end up being closer to the midpoint between the neuronal doctrine he tries to fight and the gliacentric view he pushes There s enough research and findings to point research in an exciting direction tho, and if this holds upprominent names should mention glia and The title is a bit misleading, the focus here is glia how it works and what we know, but if you are interested in neuroscience and biology at a fundamental level it will deliver The speculation is bold and the truth will likely end up being closer to the midpoint between the neuronal doctrine he tries to fight and the gliacentric view he pushes There s enough research and findings to point research in an exciting direction tho, and if this holds upprominent names should mention glia and astrocyte signalling as an important piece of the puzzle, not just connectomes and bridging the computational level to our theoretical understanding


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